:51:02
Yeah.
:51:05
Why not plumbing?
:51:07
Why not run a lube rack
for all the surgeons know about...
:51:10
Homo sapiens sapiens?
:51:12
No way.
Cancer's the only thing I ever wanted.
:51:16
No, really, cancer is...
:51:21
Awesome?
:51:22
Yeah.
:51:23
It is awesome. How does it do it?
:51:27
The intercellular regulatory mechanisms...
:51:29
especially for proliferation
and differentiation.
:51:32
- The malignant neoplasia just don't get it.
- Neoplasia, cancer cells.
:51:36
Yes, that's right.
:51:38
You grow normal cells
in a tissue culture in a lab...
:51:40
and they replicate enough
to form a confluent monolayer...
:51:43
and then divide 20 or 50 times,
but eventually they conk out.
:51:47
You grow cancer cells
and they never stop.
:51:51
No contact inhibition whatsoever,
they just pile up.
:51:54
They keep replicating forever.
:51:57
It's got a great name.
Know what it's called?
:52:00
- No, what?
- Immortality in culture.
:52:03
That sounds like a symposium.
:52:05
It's an error in judgment,
in a molecular way.
:52:09
But why?
:52:10
Even on a protistic level
the normal cell-cell interactions...
:52:14
are so subtle,
they take your breath away.
:52:17
It's incredible, it's perfect.
:52:20
What's up with cancer cells?
Smartest guys in the world...
:52:23
the best labs, funding...
:52:26
They don't know what to make of it.
:52:28
- What about you?
- Me?
:52:31
I've got some things I'm kicking around.
:52:33
Wait till I get a lab of my own,
if I can survive this fellowship.
:52:37
The part with the human beings.
:52:39
Everybody has to do it,
all the best researchers.
:52:42
They want us to converse
intelligently with clinicians...
:52:44
as if researchers were the impediment.
:52:47
Clinicians are such troglodytes.
Just cut the crap, I say.
:52:51
Are you going to be sorry when...
:52:57
Do you ever miss people?